How Long Does It Take For Trifexis To Kill Fleas

Almost everyone has a pet. For some, pets are their best friends. Almost every cat owner has a problem with fleas. Fleas are an insect that feeds on the blood of humans and animals. They have been known to transmit diseases like plague and typhus. While your cat is scratching and biting himself, it also exposes him to infections which could prove fatal if not treated on time. Fleas usually infest households and can spread really quickly.

Flea treatments can take anywhere from 24 to 48 hours to start working. Trifexis is different, though. It’s a chewable tablet that starts killing fleas within 30 minutes of administration. That’s because it contains three separate active ingredients: lufenuron, milbemycin oxime, and spinosad.

Lufenuron works by inhibiting insect growth hormones, which prevents fleas from reaching maturity and reproducing. Milbemycin oxime is a type of antibiotic that stops fleas from developing resistance to other antibiotics—and also kills adult fleas. Spinosad is an insecticide that works like a nerve poison on the flea’s central nervous system—killing them quickly and effectively. Trifexis is an oral medication that prevents heartworm disease, treats and controls adult hookworms, roundworms, and whipworms, and kills fleas. It does not protect against ticks.

The following table summarizes the length of time it takes for Trifexis to kill fleas:

– For dogs weighing over 25 lbs., it takes about 5-8 hours for Trifexis to be absorbed into the bloodstream and begin to kill fleas.

– For dogs weighing between 10-25 lbs., it takes about 6-10 hours for Trifexis to be absorbed into the bloodstream and begin to kill fleas.

– For puppies less than 10 lbs., it takes about 10-12 hours for Trifexis to be absorbed into the bloodstream and begin to kill fleas

Trifexis is a topical flea and ticks medication that is applied to your dog’s skin every month. It’s used for dogs weighing between 2 and 25 pounds and can be safely used for up to 4 weeks after giving birth or having puppies. The dosage is based on your dog’s weight, so if you want to give your dog the full dose, you’ll need to take into account how much he weighs.

The medication starts working within hours of being applied. It kills adult fleas within 12 hours of being applied and kills ticks within 24 hours of being applied.

Why Does My Dog Still Have Fleas After Using Trifexis?

Fleas can be a problem for your dog, but they don’t have to be. Trifexis is a great way to prevent fleas on dogs and eliminate existing fleas. It’s easy to use, and it comes in a variety of packages to suit your needs.

But what if you’re using Trifexis and your dog still has fleas? Well, there are several reasons why this could happen. The first thing you should do is check the expiration date on the package of Trifexis that you bought. If it’s expired, then it won’t work as well as it should, and your dog could still have fleas.

Another reason why your dog might still have flea problems after using Trifexis is that he may have been exposed to an area with an active infestation before taking the medicine. If this happens, you might need something stronger than Trifexis to get rid of those pesky critters.

Does Trifexis Kill Fleas and Eggs?

Trifexis is a flea and ticks medication that can be given to dogs. It is made by Zoetis and is available in pill form. The medication contains three active ingredients: lufenuron, milbemycin oxime, and spinosad. Trifexis is used to prevent fleas, ticks, and heartworm in dogs. In fact, it can treat more than one of these conditions at once.

In addition to killing adult fleas and ticks, Trifexis also kills flea eggs when they are ingested by a dog after eating infected feces or dirt from a host animal. The treatment does not kill ticks that have already attached themselves to a dog, but it does slow down the growth of larvae.

How Do I Know if Flea Treatment Is Working?

Sometimes it’s hard to tell if flea treatment is working. But there are a few signs you can look for to make sure your flea treatment is working properly.

First, you’ll want to pay attention to how your dog is acting. If they’re scratching a lot, or if they seem like they’re uncomfortable in any way, then you may want to talk with your vet and see if they can recommend an alternative method of flea control.

You’ll also want to look out for flea dirt and eggs on your dog’s coat. If you see them anywhere on their body, this could be a sign that your dog has been infected by fleas and needs additional treatment.

Finally, if two weeks have passed since applying the medication, you still see no signs of fleas or eggs on your pet’s coat and they no longer seem uncomfortable or irritated by the presence of these parasites in their environment, then it may be safe to assume that their environment is free from infestation and they no longer require treatment (though we always recommend checking with a professional).

Do You Have to Give Trifexis Every Month?

The answer to this question is: no. You do not need to give Trifexis every month. While it is recommended, you can also space out the doses as needed.

Trifexis is a monthly treatment for flea, tick, and heartworm prevention in dogs over 6 weeks of age. It’s made by Elanco, the same company that makes CERENIA for dogs.

Trifexis works by killing adult fleas and ticks within 24 hours of administration and eliminating 98-100 percent of fleas on your pet within 48 hours after the first dose. It also kills any flea eggs your dog might have ingested while grooming himself, which means they’re less likely to hatch into larvae later on down the line (and bite your pup).

It also kills adult heartworms within 30 days of administering the first dose, reducing their numbers so much that they’re unable to reproduce or cause any damage to your dog’s heart or other organs after that point in time (assuming he doesn’t get reinfected with another strain of heartworm).

List of Flea Killers

Fleas are a common problem in most households. They can be found on your pets and in your home, and they can cause serious health problems if left untreated.

The good news is that there are many different flea treatments available that can help you get rid of fleas from your pet and your home. You might have heard about some of them, but others might be new to you. If you don’t know where to start, this guide will give you an overview of the best products for getting rid of fleas in a safe way.


Vet’s Best Flea and Tick Home Spray | Flea Treatment for Dogs and Home | Plant-Based Formula | 32 Ounces

Price: $9.97

Features :

  • GENTLE PROTECTION: Vet’s Best Flea & Tick Home Spray uses certified natural ingredients to kill fleas, flea eggs, and ticks on contact.
  • PROVEN EFFECTIVE: Whether facing an active infestation or applying for routine prevention, our spray is scientifically proven effective against pests but gentle enough to use around the whole family.
  • CERTIFIED NATURAL OILS: Each steam-distilled essential oil is selected for its potent pest-fighting properties and is 100% Certified Natural.
  • TOTAL HOME DEFENSE: Applies easily on surfaces, indoors and out, including dog bedding, crates, furniture, blankets, upholstery, carpets, outdoor surfaces, and more. Also gentle enough to be applied directly on dogs and puppies 12 weeks or older.
  • MADE IN THE USA: Our products are proudly manufactured in the USA with quality domestic and internationally sourced ingredients.

Additional Info :

Item Dimensions 
Height0.81 Inches
Width3.38 Inches
Length3.38 Inches
Weight2.42 Pounds

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TevraPet Naturals Flea and Tick Prevention for Dogs Chewable Tablets | 120 Count | Chicken Flavor | Made in USA | Safe and Effective

TevraPet Naturals Flea and Tick Prevention for Dogs Chewable Tablets | 120 Count | Chicken Flavor | Made in USA | Safe and Effective

Price: $18.87 ($0.16 / Count)

Features :

  • Natural Protection from Fleas and Ticks – Our delicious chews provide potent prevention against fleas and ticks without exposing your dog (or your family) to harsh chemicals
  • Delicious Chicken Flavor – We’ve carefully formulated these chews to ensure that dogs will love them
  • Powered by Nature – Our chews use a powerful blend of garlic, brewer’s yeast, and folic acid to repel and kill fleas, ticks, and biting flies
  • Safe For the Whole Family – These chews are 100% natural and safe for humans and pets of all ages and sizes – giving you peace of mind that your pooch is protected – and so is your family
  • 120 Count, Proudly Made in the USA – Each bottle contains 120 tablets made with care and rigorous attention to detail right here in the USA. We stand behind all our products with our TevraPet guarantee – we will always go the extra mile to ensure your pet is protected and you are happy

Additional Info :

Item Dimensions 
Weight0.423125 Pounds

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SPECTRUM BRANDS 53944, 10-Pound Spectracide Triazicide Insect Killer for Lawns Granules 10 Pounds, Kil, 10 lbs

SPECTRUM BRANDS 53944, 10-Pound Spectracide Triazicide Insect Killer for Lawns Granules 10 Pounds, Kil, 10 lbs

Price: $7.09

Features :

  • KILLS LAWN INSECTS: Use outdoors on lawns and as a band treatment around your house foundation
  • KILLS MORE THAN 100 INSECT TYPES: Kills insects above and below ground, including ants (excluding harvester and pharaoh ants), crickets, armyworms, cutworms, grubs, ticks, and others as listed
  • KILLS ON CONTACT: Treat when insects first appear or when you notice lawn damage
  • GRANULAR FORMULA: Distribute granules uniformly around the treatment area; water in lightly immediately after application.
  • CONTROLS GRUBS: Apply when insects and grubs are active in the lawn and soil

Additional Info :

Item Dimensions 
Height18.75 Inches
Width2.75 Inches
Length11 Inches
Weight10 Pounds

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Liquid-Vet Flea & Tick+ Advanced Powerful Flea and Tick Prevention for Dogs with Natural Ingredients and Plant Extracts - Food-Grade Topical Dog Flea Treatment for Dogs 12 Weeks and Older Made in USA

Liquid-Vet Flea & Tick+ Advanced Powerful Flea and Tick Prevention for Dogs with Natural Ingredients and Plant Extracts – Food-Grade Topical Dog Flea Treatment for Dogs 12 Weeks and Older Made in USA

Price: $12.99 ($1.62 / Fl Oz)

Features :

  • 100% HOLISTIC FORMULA – The Liquid-Vet K9 Flea & Tick + Advanced provides holistic pest protection for dogs without using a fear-inducing spray or typical oral pesticides. With just a few pumps of the solution, you can prevent fleas, ticks, and mosquitoes from coming in contact with your dogs.
  • WITH NATURAL INGREDIENTS – Its powerful plant extracts, including Eugenol, Geraniol, Thyme oil, Lemongrass Oil, Peppermint oil, and Rosemary oil, offer safe and effective application. All the ingredients are 100% Food-Grade, to ensure safety for your dog and your family.
  • PERMETHRIN AND FIPRONIL-FREE – No registered pesticides are added to our formula unlike most Flea and Tick Sprays and Spot-On Treatments. Plus, it leaves no oily residue on your pet or your furniture. The best part is that it leaves an incredibly fresh scent on your pet.
  • SUPER EASY TO APPLY – Simply rub evenly in the tail, legs, and stomach avoiding private parts and the face area. Apply once a week for maintenance or daily for infestations. Reapply after bathing and swimming. A single bottle of our Dog Flea Treatment can last up to 12 months.
  • MADE IN THE USA – Liquid-Vet Flea & Tick is manufactured at our own plant located in the USA, using materials only from our qualified USA-based suppliers. Therefore, at Liquid-Vet, Quality Control is # 1. We back that with a 100% NO Questions Asked Money Back Guarantee on all formulas.

Additional Info :

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In Conclusion,

Trifexis is an oral medication that kills fleas and prevents heartworm disease in dogs. It also protects against ticks, prevents intestinal parasites and roundworms, and treats whipworm infections.

The treatment takes effect within one month of the initial dose, but it can take up to three months for all of its components to be completely effective. The drug will continue to protect your dog from heartworm disease for as long as it’s taken.

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